T细胞和B细胞联合急性淋巴细胞白血病
Combined T and B cell acute lymphoblastic leukaemia.
作者信息
Haegert D G, Cawley J C, Karpas A, Goldstone A H
出版信息
Br Med J. 1974 Oct 12;4(5936):79-82. doi: 10.1136/bmj.4.5936.79.
Abstract
A case of acute lymphoblastic leukaemia in a 17-year-old male is described. The patient had many distinctive features including a very high blast cell count, prominent lymphadenopathy and hepatosplenomegaly, thymic mass, and a fulminant clinical course. Immunological studies on the blast cells using a variety of techniques showed the presence of two distinct subpopulations, one having the surface characteristics of thymus-dependent (T) lymphoid cells and the other those of bursa-equivalent (B) lymphoid cells. The case therefore represents the first example of a combined T and B cell acute leukaemia.
摘要
本文描述了一名17岁男性急性淋巴细胞白血病病例。该患者具有许多独特特征，包括原始细胞计数极高、显著的淋巴结病和肝脾肿大、胸腺肿块以及暴发性临床病程。使用多种技术对原始细胞进行的免疫学研究显示存在两个不同的亚群，一个具有胸腺依赖性（T）淋巴细胞的表面特征，另一个具有法氏囊等效（B）淋巴细胞的表面特征。因此，该病例代表了首例T细胞和B细胞联合急性白血病。
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Peripheral blood T- and B-lymphocytes in patients with lymphoma and acute leukemia.淋巴瘤和急性白血病患者的外周血T淋巴细胞和B淋巴细胞
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