噬菌体μ的温度敏感突变体
Temperature-sensitive mutants of bacteriophage mu.
作者信息
Bukhari A I, Curtin P
出版信息
J Virol. 1974 Dec;14(6):1615-6. doi: 10.1128/JVI.14.6.1615-1616.1974.
Abstract
Temperature-sensitive mutants of bacteriophage Mu, which grow at 32 C but not at 42 C, have been isolated. These mutants fall into two groups. Group 1 mutants fail to lyse host cells at nonpermissive temperatures, whereas lysis occurs normally with the group 2 mutants. All of the group 1 mutants apparently belong to the cistrons mapping to the left of gene C, whereas the group 2 mutants have lesions in various genes between D and S.
摘要
已经分离出噬菌体Mu的温度敏感突变体，它们在32℃时生长，但在42℃时不生长。这些突变体分为两组。第1组突变体在非允许温度下不能裂解宿主细胞，而第2组突变体则能正常发生裂解。所有第1组突变体显然都属于位于基因C左侧的顺反子，而第2组突变体在D和S之间的各种基因中存在损伤。
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Proc Natl Acad Sci U S A. 1963 Dec;50(6):1043-51. doi: 10.1073/pnas.50.6.1043.
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