Kane S P, Parkins R A
Postgrad Med J. 1979 Mar;55(641):215-7. doi: 10.1136/pgmj.55.641.215.
A patient is presented who, in addition to subtotal villous atrophy, had superficial ulcers of the jejunum, as well as a wide band of granulation tissue deep to the crypts suggesting recurrent past ulceration. In spite of these changes she had no intestinal symptoms at the time of her presentation with reflux oesophagitis, and her only nutritional abnormality was a mild folate deficiency. Withdrawal of dietary gluten produced some improvement of the jejunal mucosa but this was not sustained on continued low-grade ingestion. She has containued to be virtually symptom-free over a 3-year period of follow-up.
现报告一例患者，除了绒毛萎缩不全外，空肠还有浅表溃疡，并且在隐窝深部有一条宽的肉芽组织带，提示既往有复发性溃疡。尽管有这些改变，但她在因反流性食管炎就诊时并无肠道症状，其唯一的营养异常是轻度叶酸缺乏。去除饮食中的麸质后，空肠黏膜有一定改善，但在持续少量摄入麸质的情况下，这种改善未能持续。在3年的随访期间，她几乎一直没有症状。
