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血红蛋白D旁遮普型(D洛杉矶型)

Haemoglobin D Punjab (D Los Angeles).

作者信息

Vella F, Lehmann H

出版信息

J Med Genet. 1974 Dec;11(4):341-8. doi: 10.1136/jmg.11.4.341.

Abstract

A search for haemoglobin variants undertaken in Canada revealed 21 unrelated instances of Hb D Punjab amongst 207,300 specimens tested. Of these, eight came from East Indian immigrants and the rest from Canadians of United Kingdom origin. No instances of Hb D Punjab were found in 14,500 specimens from Canadian Indians that were tested. The geographical origins of 27 instances of Hb D Punjab characterized at the MRC Abnormal Haemoglobin Unit, Cambridge are presented. Of these five were natives of the British Isles. The results of surveys undertaken in the United Kingdom are summarized. The global distribution of Hb D Punjab is discussed.

摘要

在加拿大开展的一项血红蛋白变体研究发现,在检测的207,300份样本中有21例不相关的血红蛋白D旁遮普变体。其中,8例来自东印度移民,其余来自祖籍英国的加拿大人。在检测的14,500份加拿大印第安人样本中未发现血红蛋白D旁遮普变体。本文介绍了在剑桥医学研究委员会异常血红蛋白研究室鉴定的27例血红蛋白D旁遮普变体的地理来源。其中5例来自不列颠群岛。总结了在英国开展的调查结果。并讨论了血红蛋白D旁遮普变体在全球的分布情况。

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本文引用的文献

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