Mirkova E, Mikhaĭlova A
Probl Khig. 1979;4:20-5.
The influence of the herbicide balagrin on the maternal organism and fetus was experimentally studied on 60 pregnant albino rats of Wistar line. The preparation was given orally throughout the entire gestation period in daily doses of 1/1o - 110 mg/kg, 1/20 - 55 mg/kg and 1/50 - 22 mg/kg of LD50 - 1100 mg/kg. The detoxifying function was studied by the duration of hexabarbital sleep, the excretory function - by the cholic acid content in the bile, and the enzymatic function - by the dehydrogenase activities: LDH, MDH, LDH, GL-6-PDH in the liver of pregnant animals and the fetus, Marked toxic effect on the maternal and fetal organism was demonstrable at all balagrin application levels by the liver function disturbances.
在60只Wistar系怀孕白化大鼠身上，通过实验研究了除草剂巴拉格灵对母体和胎儿的影响。在整个妊娠期内，以LD50为1100mg/kg的1/10 - 110mg/kg、1/20 - 55mg/kg和1/50 - 22mg/kg的日剂量口服该制剂。通过己巴比妥睡眠时间研究解毒功能，通过胆汁中胆酸含量研究排泄功能，通过脱氢酶活性研究酶功能：怀孕动物和胎儿肝脏中的LDH、MDH、LDH、GL - 6 - PDH。在所有巴拉格灵应用水平下，均通过肝功能紊乱对母体和胎儿机体表现出明显的毒性作用。
