恶喹酸治疗尿路感染：一项多中心试验
Oxolinic acid in urinary tract infection: a multi-centre trial.
作者信息
Guyer B M, Whitford G M
出版信息
Curr Med Res Opin. 1974;2(10):636-40. doi: 10.1185/03007997409111876.
PMID:4616804
Abstract
A single-blind trial of oxolinic acid (750 mg. twice-daily for 14 days) and ampicillin (500 mg. 3-times daily for 14 days) in 60 cases with urinary tract symptoms showed superior results with oxolinic acid: 94% of pathogens were sensitive to oxolinic acid and 69% were sensitive to ampicillin. Sympotomatic relief and bacterial eradication occurred earlier in the oxolinic acid group.
摘要
一项针对60例有尿路症状患者的单盲试验，对比了恶喹酸（每日两次，每次750毫克，共14天）和氨苄西林（每日三次，每次500毫克，共14天）的疗效，结果显示恶喹酸效果更佳：94%的病原体对恶喹酸敏感，69%对氨苄西林敏感。恶喹酸组的症状缓解和细菌清除出现得更早。
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