Bedryshev G D, Masiuk A I
Tsitol Genet. 1974 Sep-Oct;8(5):452-64.
A review of literature and the authors own data on specific and non-specific effect of DNA on the organism and eucaryote cells are presented. A conclusion is made that transduction and transformation in eucaryotes might be possible. It is confirmed by a great number of experimental data. The problem on mutagenic effect of DNA still remains disputable. The problem of DNA restriction in eucaryotes is absolutely unstudied and requires experimental development. A great theoretical and practical significance of the studies in the effect of exogenic DNA in higher organisms is emphasized.
本文综述了有关DNA对生物体和真核细胞的特异性和非特异性作用的文献以及作者自己的数据。得出的结论是,真核生物中的转导和转化可能是可行的。大量实验数据证实了这一点。DNA的诱变作用问题仍然存在争议。真核生物中DNA限制的问题完全未被研究,需要进行实验探索。强调了研究外源DNA对高等生物作用的重大理论和实践意义。