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Inability of imipramine to protect against type A or type B monoamine oxidase inhibition by pargyline.

作者信息

Fuller R W, Hemrick S K

出版信息

Res Commun Chem Pathol Pharmacol. 1979 Feb;23(2):411-4.

PMID:461967
Abstract

Imipramine (30 mg/kg i.p.) did not antagonize the inhibition of either type A or type B MAO by pargyline in brain, heart or liver of rats. Occupancy of active sites on mitochondrial MAO by imipramine probably does not occur at doses of imipramine adequate to inhibit monoamine uptake.

摘要

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