Naef A P
Schweiz Med Wochenschr. 1979 Jun 2;109(22):816-9.
Surgical resection is the most efficient therapy for lung cancer. Preoperative investigation should determine histology, local invasion and distant dissemination. Tumor-host relation (immunocompetence and tumor burden) is essential for long-term results. Relatively crude anatomical staging does not take biological parameters into account, and any case with lympho-glandular involvement (N1) should not be considered as stage I carcinoma. 520 cases treated by pulmonary resection are reviewed and common denominators for long-term survivors determined. Stage I epidermoid carcinoma treated by lobectomy or left pneumonectomy with a short history (survey cases) are the ideal candidates for surgical resection. The importance of early diagnosis by routine screening is stressed.
手术切除是肺癌最有效的治疗方法。术前检查应确定组织学类型、局部侵犯和远处转移情况。肿瘤与宿主的关系(免疫能力和肿瘤负荷)对长期治疗效果至关重要。相对粗略的解剖学分期未考虑生物学参数,任何伴有淋巴结受累(N1)的病例都不应被视为I期癌。对520例行肺切除术治疗的病例进行回顾,并确定长期存活者的共同特征。I期表皮样癌采用肺叶切除术或左全肺切除术且病程较短(普查病例)者是手术切除的理想对象。强调了通过常规筛查进行早期诊断的重要性。