正常小鼠血清中与酶消化的γ球蛋白反应的抗球蛋白因子。
Antiglobulin factors in normal mouse serum reacting with enzyme-digested gamma globulin.
作者信息
Measel J W, Cozad G C
出版信息
Infect Immun. 1975 Feb;11(2):290-3. doi: 10.1128/iai.11.2.290-293.1975.
Abstract
The presence of antiglobulin factors in normal mouse serum was studied. Mice were injected with human 0 Rh(+) erythrocytes and the resulting gamma globulins were digested with papain. The reaction was demonstrated by agglutinations of human 0 Rh (+) perythryocytes sensitized with the Fab fragments when treated with normal mouse serum. Studies suggested that there are two factors in mice, a 7S AND A 19S globulin form. Cross-reactivity between strains of mice was demonstrated.
摘要
对正常小鼠血清中抗球蛋白因子的存在情况进行了研究。给小鼠注射人O型Rh（+）红细胞，然后用木瓜蛋白酶消化产生的γ球蛋白。当用正常小鼠血清处理时，用Fab片段致敏的人O型Rh（+）红细胞的凝集反应证明了该反应。研究表明，小鼠中有两种因子，一种是7S球蛋白形式，另一种是19S球蛋白形式。还证明了不同品系小鼠之间存在交叉反应。
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