用多价链霉素依赖型大肠杆菌疫苗进行口服免疫。
Oral immunization with polyvalent streptomycin-dependent Escherichia coli vaccine.
作者信息
Felsenfeld O, Wolf R H, Greer W E, Brannon R B
出版信息
Appl Microbiol. 1972 Mar;23(3):444-8. doi: 10.1128/am.23.3.444-448.1972.
Abstract
Streptomycin-dependent Escherichia coli serotypes O 111, O 55 and O 26 were used to vaccinate young patas monkeys against these organisms by the oral route. Five administrations of 10(10) cells in 3-day intervals gave almost full protection to the animals against challenge with 9 to 11 minimal infective doses of homologous virulent organisms for at least 1 month, whether the three serotypes were administered singly or simultaneously.
摘要
利用对链霉素依赖的大肠杆菌血清型O 111、O 55和O 26，通过口服途径对幼小的粗尾猿猴进行针对这些微生物的疫苗接种。以3天的间隔给予5次每次10¹⁰个细胞的剂量，无论这三种血清型是单独给药还是同时给药，都能使动物几乎完全免受9至11个最小感染剂量的同源有毒微生物的攻击，保护期至少为1个月。
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Studies on vaccination against bacillary dysentery. 1. Immunization of mice against experimental Shigella infection.关于细菌性痢疾疫苗接种的研究。1. 小鼠针对实验性志贺氏菌感染的免疫接种。
Bull World Health Organ. 1965;32(5):633-6.
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[New contributions relative to the role of "R" antibodies in natural immunity].关于“R”抗体在自然免疫中作用的新贡献
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[Laboratory experiments on the possibilities of oral immunization with sodium desoxycholate extract from Dyspepsia coli strains. X. The behavior of the extract with reference to the influence of the gastric juice and the chemical composition of the extract].
Zentralbl Bakteriol Orig. 1970;213(2):193-200.
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[Oral immunization against coli enteritis with streptomycin-dependent E. coli. IV. Tolerance of a streptomycin-dependent O111 B4 bacterial vaccine in infants].
Zentralbl Bakteriol Orig. 1969;211(4):486-93.
7
[Oral immunization against coli enteritis with streptomycin-dependent E. coli. I. Characterization of streptomycin-dependent vaccinal strains].
Zentralbl Bakteriol Orig. 1969;211(4):453-65.
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