低丙种球蛋白血症和选择性IgA缺乏症患者的血清IgE浓度。对患者及其家庭成员的研究。
Serum IgE concentrations in hypogammaglobulinaemia and selective IgA deficiency. Studies on patients and family members.
作者信息
Stites D P, Ishizaka K, Fudenberg H H
出版信息
Clin Exp Immunol. 1972 Mar;10(3):391-7.
Abstract
Serum IgE levels in twelve patients with adult `acquired' hypogammaglobulinaemia were markedly reduced. In addition, seventeen of fifty first degree relatives and spouses had low IgE levels. IgE levels varied among patients with selective IgA deficiency and a combined deficiency did not necessarily predispose to recurrent infections. This study suggests that the absence of IgE in certain immune deficiency states does not, by itself, decrease resistance to infection.
摘要
12例成人“获得性”低丙种球蛋白血症患者的血清IgE水平显著降低。此外，50名一级亲属和配偶中有17人的IgE水平较低。选择性IgA缺乏患者的IgE水平各不相同，联合缺乏并不一定会导致反复感染。这项研究表明，在某些免疫缺陷状态下IgE的缺乏本身并不会降低对感染的抵抗力。
相似文献
1
2
Hypogammaglobulinaemia in the United Kingdom. V. Immunoglobulins in hypogammaglobulinaemia.英国的低丙种球蛋白血症。五、低丙种球蛋白血症中的免疫球蛋白
Spec Rep Ser Med Res Counc (G B). 1971;310:45-66.
3
Incidence of isolated deficiency of IgA in the serum of Canadian children.加拿大儿童血清中孤立性IgA缺乏症的发病率。
Ann Allergy. 1972 Jan;30(1):11-23.
4
Serum IgE in immune deficiency disorders.免疫缺陷疾病中的血清免疫球蛋白E
Clin Exp Immunol. 1974 Mar;16(3):375-81.
5
[IgA deficiency: clinical ans immunological evaluation of 28 patients].
Tijdschr Kindergeneeskd. 1992 Apr;60(2):31-5.
6
[Serum immunoglobulins in scabies].
Hautarzt. 1982 Jun;33(6):329-30.
7
Serum IgD and IgE concentrations in immunodeficiency diseases.免疫缺陷疾病中的血清IgD和IgE浓度。
J Clin Invest. 1975 Jan;55(1):157-65. doi: 10.1172/JCI107906.
8
9
[Study of a case of severe congenital primary, non-sex-linked hypogammaglobulinemia of probable genetic origin. Familial survey].
Nouv Rev Fr Hematol. 1972 Jan-Feb;12(1):101-10.
10
X-linked hypogammaglobulinemia. Additional observations in a previously reported family.
Isr J Med Sci. 1971 Nov;7(11):1280-5.
引用本文的文献
1
The Very Low IgE Producer: Allergology, Genetics, Immunodeficiencies, and Oncology.极低IgE产生者：过敏学、遗传学、免疫缺陷与肿瘤学
Biomedicines. 2023 May 6;11(5):1378. doi: 10.3390/biomedicines11051378.
2
Diagnostic Challenges in Patients with Inborn Errors of Immunity with Different Manifestations of Immune Dysregulation.免疫缺陷病患者免疫调节异常不同表现形式的诊断挑战
J Clin Med. 2022 Jul 20;11(14):4220. doi: 10.3390/jcm11144220.
3
Spectrum of Disease Manifestations in Patients with Selective Immunoglobulin E Deficiency.选择性免疫球蛋白E缺乏症患者的疾病表现谱
J Clin Med. 2021 Sep 15;10(18):4160. doi: 10.3390/jcm10184160.
4
Low Serum IgE Is a Sensitive and Specific Marker for Common Variable Immunodeficiency (CVID).低血清 IgE 是常见变异性免疫缺陷（CVID）的敏感且特异的标志物。
J Clin Immunol. 2018 Apr;38(3):225-233. doi: 10.1007/s10875-018-0476-0. Epub 2018 Feb 17.
5
Immunoglobulin E-an Innocent Bystander in Host Defense?免疫球蛋白E——宿主防御中的无辜旁观者？
J Clin Immunol. 2018 Apr;38(3):223-224. doi: 10.1007/s10875-018-0482-2. Epub 2018 Feb 15.
6
Selective IgE deficiency and cardiovascular diseases.选择性IgE缺乏与心血管疾病。
Allergy Asthma Proc. 2015 May-Jun;36(3):225-9. doi: 10.2500/aap.2015.36.3825.
7
[Radioimmunologic determination of immunoglobulin E (author's transl)].免疫球蛋白E的放射免疫测定（作者译）
Klin Wochenschr. 1974 Jan 1;52(1):18-23. doi: 10.1007/BF01468517.
8
Family studies in immunoglobulin levels.免疫球蛋白水平的家族研究。
Clin Exp Immunol. 1974 Jan;16(1):13-21.
9
Immunoglobulin in health and disease. III. Immunoglobulins in the sera of patients with amoebiasis.健康与疾病中的免疫球蛋白。III. 阿米巴病患者血清中的免疫球蛋白
Clin Exp Immunol. 1974 Feb;16(2):163-8.
10
[Immunoglobulin E. Biochemical, immunological properties and clinical significance (author's transl)].[免疫球蛋白E。生化、免疫学特性及临床意义（作者译）]
Klin Wochenschr. 1974 Jan 1;52(1):1-17. doi: 10.1007/BF01468516.
本文引用的文献
1
ADULT HYPOGAMMAGLOBULINEMIA. ANALYSIS OF 100 CASES.
Am J Med. 1964 Apr;36:618-23. doi: 10.1016/0002-9343(64)90108-1.
2
Clinical investigation of patients with agammaglobulinemia and hypogammaglobulinemia.无丙种球蛋白血症和低丙种球蛋白血症患者的临床研究。
Pediatr Clin North Am. 1960 May;7:397-433. doi: 10.1016/s0031-3955(16)30945-2.
3
IgE concentrations in children with atopic diseases. A clinical study.特应性疾病患儿的IgE浓度。一项临床研究。
Int Arch Allergy Appl Immunol. 1969;36(3):219-32. doi: 10.1159/000230745.
4
Clinical, serologic and leukocyte function studies on patients with idiopathic "acquired" agammaglobulinemia and their families.
Am J Med. 1970 Jan;48(1):48-53. doi: 10.1016/0002-9343(70)90097-5.
5
Serum IgE concentrations and skin reactivity to anti-IgE antibody in IgA-deficient patients.IgA 缺乏患者的血清 IgE 浓度及对抗 IgE 抗体的皮肤反应性。
N Engl J Med. 1971 Mar 11;284(10):513-7. doi: 10.1056/NEJM197103112841002.
6
Immunochemical quantitation of antigens by single radial immunodiffusion.通过单向辐射免疫扩散法对抗原进行免疫化学定量。
Immunochemistry. 1965 Sep;2(3):235-54. doi: 10.1016/0019-2791(65)90004-2.
7
Serum levels of immune globulins in health and disease: a survey.健康与疾病状态下血清免疫球蛋白水平：一项调查
Pediatrics. 1966 May;37(5):715-27.
8
Healthy IgE-deficient person.健康的免疫球蛋白E缺乏者。
N Engl J Med. 1970 Sep 3;283(10):541-2. doi: 10.1056/nejm197009032831018.
9
Immune deficiency and IgE.
Lancet. 1970 Mar 21;1(7647):627-8. doi: 10.1016/s0140-6736(70)91680-6.
10
Immunoglobulin levels during childhood, with special regard to IgE.儿童期的免疫球蛋白水平，特别关注免疫球蛋白E
Acta Paediatr Scand. 1969 Sep;58(5):513-24. doi: 10.1111/j.1651-2227.1969.tb04753.x.
Zotero 插件