低丙种球蛋白血症和选择性IgA缺乏症患者的血清IgE浓度。对患者及其家庭成员的研究。
Serum IgE concentrations in hypogammaglobulinaemia and selective IgA deficiency. Studies on patients and family members.
作者信息
Stites D P, Ishizaka K, Fudenberg H H
出版信息
Clin Exp Immunol. 1972 Mar;10(3):391-7.
Abstract
Serum IgE levels in twelve patients with adult `acquired' hypogammaglobulinaemia were markedly reduced. In addition, seventeen of fifty first degree relatives and spouses had low IgE levels. IgE levels varied among patients with selective IgA deficiency and a combined deficiency did not necessarily predispose to recurrent infections. This study suggests that the absence of IgE in certain immune deficiency states does not, by itself, decrease resistance to infection.
摘要
12例成人“获得性”低丙种球蛋白血症患者的血清IgE水平显著降低。此外，50名一级亲属和配偶中有17人的IgE水平较低。选择性IgA缺乏患者的IgE水平各不相同，联合缺乏并不一定会导致反复感染。这项研究表明，在某些免疫缺陷状态下IgE的缺乏本身并不会降低对感染的抵抗力。
相似文献
1
Serum IgE concentrations in hypogammaglobulinaemia and selective IgA deficiency. Studies on patients and family members.
Clin Exp Immunol. 1972 Mar;10(3):391-7.
2
Hypogammaglobulinaemia in the United Kingdom. V. Immunoglobulins in hypogammaglobulinaemia.
Spec Rep Ser Med Res Counc (G B). 1971;310:45-66.
3
Incidence of isolated deficiency of IgA in the serum of Canadian children.
Ann Allergy. 1972 Jan;30(1):11-23.
4
Serum IgE in immune deficiency disorders.
Clin Exp Immunol. 1974 Mar;16(3):375-81.
5
[IgA deficiency: clinical ans immunological evaluation of 28 patients].
Tijdschr Kindergeneeskd. 1992 Apr;60(2):31-5.
6
[Serum immunoglobulins in scabies].
Hautarzt. 1982 Jun;33(6):329-30.
7
Serum IgD and IgE concentrations in immunodeficiency diseases.
J Clin Invest. 1975 Jan;55(1):157-65. doi: 10.1172/JCI107906.
8
Human faecal immunoglobulins in healthy infants and children, and in some with diseases affecting the intestinal tract or the immune system.
Clin Exp Immunol. 1975 Nov;22(2):210-22.
9
[Study of a case of severe congenital primary, non-sex-linked hypogammaglobulinemia of probable genetic origin. Familial survey].
Nouv Rev Fr Hematol. 1972 Jan-Feb;12(1):101-10.
10
X-linked hypogammaglobulinemia. Additional observations in a previously reported family.
Isr J Med Sci. 1971 Nov;7(11):1280-5.
引用本文的文献
1
The Very Low IgE Producer: Allergology, Genetics, Immunodeficiencies, and Oncology.
Biomedicines. 2023 May 6;11(5):1378. doi: 10.3390/biomedicines11051378.
2
Diagnostic Challenges in Patients with Inborn Errors of Immunity with Different Manifestations of Immune Dysregulation.
J Clin Med. 2022 Jul 20;11(14):4220. doi: 10.3390/jcm11144220.
3
Spectrum of Disease Manifestations in Patients with Selective Immunoglobulin E Deficiency.
J Clin Med. 2021 Sep 15;10(18):4160. doi: 10.3390/jcm10184160.
4
Low Serum IgE Is a Sensitive and Specific Marker for Common Variable Immunodeficiency (CVID).
J Clin Immunol. 2018 Apr;38(3):225-233. doi: 10.1007/s10875-018-0476-0. Epub 2018 Feb 17.
5
Immunoglobulin E-an Innocent Bystander in Host Defense?
J Clin Immunol. 2018 Apr;38(3):223-224. doi: 10.1007/s10875-018-0482-2. Epub 2018 Feb 15.
6
Selective IgE deficiency and cardiovascular diseases.
Allergy Asthma Proc. 2015 May-Jun;36(3):225-9. doi: 10.2500/aap.2015.36.3825.
7
[Radioimmunologic determination of immunoglobulin E (author's transl)].
Klin Wochenschr. 1974 Jan 1;52(1):18-23. doi: 10.1007/BF01468517.
8
Family studies in immunoglobulin levels.
Clin Exp Immunol. 1974 Jan;16(1):13-21.
9
Immunoglobulin in health and disease. III. Immunoglobulins in the sera of patients with amoebiasis.
Clin Exp Immunol. 1974 Feb;16(2):163-8.
10
[Immunoglobulin E. Biochemical, immunological properties and clinical significance (author's transl)].
Klin Wochenschr. 1974 Jan 1;52(1):1-17. doi: 10.1007/BF01468516.
本文引用的文献
1
ADULT HYPOGAMMAGLOBULINEMIA. ANALYSIS OF 100 CASES.
Am J Med. 1964 Apr;36:618-23. doi: 10.1016/0002-9343(64)90108-1.
2
Clinical investigation of patients with agammaglobulinemia and hypogammaglobulinemia.
Pediatr Clin North Am. 1960 May;7:397-433. doi: 10.1016/s0031-3955(16)30945-2.
3
IgE concentrations in children with atopic diseases. A clinical study.
Int Arch Allergy Appl Immunol. 1969;36(3):219-32. doi: 10.1159/000230745.
4
Clinical, serologic and leukocyte function studies on patients with idiopathic "acquired" agammaglobulinemia and their families.
Am J Med. 1970 Jan;48(1):48-53. doi: 10.1016/0002-9343(70)90097-5.
5
Serum IgE concentrations and skin reactivity to anti-IgE antibody in IgA-deficient patients.
N Engl J Med. 1971 Mar 11;284(10):513-7. doi: 10.1056/NEJM197103112841002.
6
Immunochemical quantitation of antigens by single radial immunodiffusion.
Immunochemistry. 1965 Sep;2(3):235-54. doi: 10.1016/0019-2791(65)90004-2.
7
Serum levels of immune globulins in health and disease: a survey.
Pediatrics. 1966 May;37(5):715-27.
8
Healthy IgE-deficient person.
N Engl J Med. 1970 Sep 3;283(10):541-2. doi: 10.1056/nejm197009032831018.
9
Immune deficiency and IgE.
Lancet. 1970 Mar 21;1(7647):627-8. doi: 10.1016/s0140-6736(70)91680-6.
10
Immunoglobulin levels during childhood, with special regard to IgE.
Acta Paediatr Scand. 1969 Sep;58(5):513-24. doi: 10.1111/j.1651-2227.1969.tb04753.x.
Zotero 插件