Hayakawa T, Waltz A G, Jacobson R L
Stroke. 1979 May-Jun;10(3):263-7. doi: 10.1161/01.str.10.3.263.
Hypertension was produced in 8 cats by nephrectomy and wrapping the opposite kidney. Subsequent occlusion of one middle cerebral artery caused ischemic infarcts that were larger than those of 8 normotensive cats. The larger infarcts may have been caused by increases of ischemic cerebral edema resulting from changes in the cerebral endothelial barrier induced by hypertension. In addition to increasing the likelihood of strokes, hypertension in humans may predispose toward larger cerebral infarcts.
通过切除一侧肾脏并包裹另一侧肾脏，在8只猫身上诱发了高血压。随后阻断一条大脑中动脉，导致缺血性梗死灶比8只血压正常的猫更大。梗死灶增大可能是由于高血压引起的脑内皮屏障变化导致缺血性脑水肿增加所致。除了增加中风的可能性外，人类高血压可能会导致更大的脑梗死。
