Beniashvili D Sh
Tsitologiia. 1979 Jun;21(6):733-6.
Ultrastructural changes have been studied using 67 tumors originated from the Schwann cells. Tumors were induced by means of methylnitrosourea injection with a week intervals. Both benign (fascicular and reticular) and malignant neurinomes were obtained. Main morphological changes were found in the Schwann cells. The tumor cell ultrastructure appeared to be definetely related to the degree of the tumor maturity. The results obtained may suggest that the fine structure of neurogenic tumors is also characteristic of their normal prototype--the Schwann cells.
利用67个源自施万细胞的肿瘤对超微结构变化进行了研究。通过每隔一周注射甲基亚硝基脲来诱导肿瘤形成。获得了良性（束状和网状）和恶性神经鞘瘤。主要的形态学变化见于施万细胞。肿瘤细胞的超微结构似乎与肿瘤成熟程度明确相关。所获结果可能提示神经源性肿瘤的精细结构也具有其正常原型——施万细胞的特征。
