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恒河猴体内曼氏血吸虫地理株的比较

Comparison of geographical strains of Schistosoma mansoni in the rhesus monkey.

作者信息

Powers K G, Cheever A W

出版信息

Bull World Health Organ. 1972;46(3):295-300.

Abstract

Rhesus monkeys were infected with strains of Schistosoma mansoni from Puerto Rico, St Lucia, Brazil, and Tanzania. Monkeys were killed 11-14 weeks after exposure to 600-650 cercariae. Some differences in the behaviour of different strains were noted, but the similarities between the strains were more remarkable. The only strain difference observed in both mice and monkeys was a prolonged prepatent period in animals infected with the Mwanza strain. The results of experimental infections are believed to be of little value in predicting possible differences in the pathogenicity of schistosome strains for man.

摘要

恒河猴感染了来自波多黎各、圣卢西亚、巴西和坦桑尼亚的曼氏血吸虫菌株。在接触600 - 650只尾蚴11 - 14周后处死猴子。注意到不同菌株的行为存在一些差异,但菌株之间的相似性更为显著。在小鼠和猴子中观察到的唯一菌株差异是感染姆万扎菌株的动物的潜伏期延长。实验感染的结果被认为对于预测血吸虫菌株对人类致病性的可能差异价值不大。

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Quantitative comparison of the intensity of Schistosoma mansoni infections in man and experimental animals.
Trans R Soc Trop Med Hyg. 1969;63(6):781-95. doi: 10.1016/0035-9203(69)90122-9.

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