恒河猴体内曼氏血吸虫地理株的比较
Comparison of geographical strains of Schistosoma mansoni in the rhesus monkey.
作者信息
Powers K G, Cheever A W
出版信息
Bull World Health Organ. 1972;46(3):295-300.
Abstract
Rhesus monkeys were infected with strains of Schistosoma mansoni from Puerto Rico, St Lucia, Brazil, and Tanzania. Monkeys were killed 11-14 weeks after exposure to 600-650 cercariae. Some differences in the behaviour of different strains were noted, but the similarities between the strains were more remarkable. The only strain difference observed in both mice and monkeys was a prolonged prepatent period in animals infected with the Mwanza strain. The results of experimental infections are believed to be of little value in predicting possible differences in the pathogenicity of schistosome strains for man.
摘要
恒河猴感染了来自波多黎各、圣卢西亚、巴西和坦桑尼亚的曼氏血吸虫菌株。在接触600 - 650只尾蚴11 - 14周后处死猴子。注意到不同菌株的行为存在一些差异，但菌株之间的相似性更为显著。在小鼠和猴子中观察到的唯一菌株差异是感染姆万扎菌株的动物的潜伏期延长。实验感染的结果被认为对于预测血吸虫菌株对人类致病性的可能差异价值不大。
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本文引用的文献
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A comparison of Puerto Rican, Brazilian, Egyptian and Tanzanian strains of Schistosoma mansoni in mice: penetration of cercariae, maturation of schistosomes and production of liver disease.
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Schistosoma mansoni infection in rhesus monkeys: changes in egg production and egg distribution in prolonged infections in intact and splenectomized monkeys.恒河猴感染曼氏血吸虫：完整和脾切除的猴子长期感染后产卵量及虫卵分布的变化
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A comparison of the pathogenicity of two geographical strains of Schistosoma mansoni in rhesus monkeys.
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