David C S
Genetics. 1972 Aug;71(4):649-51. doi: 10.1093/genetics/71.4.649.
Chicken allotypes b1 and b2 are controlled by allelic genes and associated with the IgG class of immunoglobulins. The determinants cannot be detected on either isolated heavy and light polypeptide chains or the enzymatic fragments. The results suggest that either the intact IgG molecule is required for their expression or the conditions normally used for isolation of the subunits destroy or modify the antigenic specificities in chickens.
鸡同种异型b1和b2由等位基因控制,并与免疫球蛋白的IgG类相关。在分离的重链和轻链多肽或酶解片段上均无法检测到这些决定簇。结果表明,它们的表达需要完整的IgG分子,或者通常用于分离亚基的条件破坏或改变了鸡体内的抗原特异性。