转移因子：恒河猴对曼氏血吸虫和结核菌素的迟发型超敏反应
Transfer factor: delayed hypersensitivity to Schistosoma mansoni and tuberculin in Macaca mulatta.
作者信息
Maddison S E, Hicklin M D, Conway B P, Kagan I G
出版信息
Science. 1972 Nov 17;178(4062):757-9. doi: 10.1126/science.178.4062.757.
PMID:4628344
Abstract
Delayed hypersensitivity in Macaca mulatta infected with either Schistosoma mansoni or mycobacteria was demonstrated by biopsies of skin test sites. Both dialyzable and nondialyzable leukocyte extracts from infected donors transferred delayed hypersensitivity to recipient monkeys. In two recipients, skin test conversion was associated with in vitro transformation of the recipients' lymphocytes.
摘要
通过对皮肤试验部位进行活检，证实感染曼氏血吸虫或分枝杆菌的恒河猴存在迟发型超敏反应。来自受感染供体的可透析和不可透析白细胞提取物均可将迟发型超敏反应转移给受体猴。在两名受体中，皮肤试验转变与受体淋巴细胞的体外转化相关。
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