Vishnevskaia E E
Vopr Onkol. 1979;25(5):36-8.
The author presents an analysis of the issues of different variants of the combination treatment for cervical cancer in 551 patients. In 246 of them the therapeutic schedule included the preoperative irradiation, in 305--the postoperative one. The preoperative irradiation was conducted following the fractional-protracted and large fractional techniques. Use of the irradiation preoperatively made it feasible to increase a 5-year survival in the patients; the fractional-protracted technique, however, yielded a greater number of the postoperative complications. Irradiation conducted in the regimen of large fractionation dose allowed obviating many of these complications and retaining the advantages of the combination treatment with preoperative radiotherapy.
作者对551例宫颈癌患者不同联合治疗方案的问题进行了分析。其中246例患者的治疗方案包括术前放疗,305例患者的治疗方案包括术后放疗。术前放疗采用分次延长照射和大分割照射技术。术前放疗能够提高患者的5年生存率;然而,分次延长照射技术会导致更多的术后并发症。大分割剂量照射方案能够避免许多此类并发症,并保留术前放疗联合治疗的优势。