[下丘脑电刺激对患有布朗-皮尔斯癌的家兔血液中11-羟基皮质类固醇含量及免疫指标的影响]
[Effect of hypothalamic electrostimulation on the 11-hydroxy-corticosteroid content in the blood and on the immunological indices in rabbits with Brown-Pearce carcinoma].
作者信息
Balitskiĭ K P, Vinitskiĭ V B, Veksler I G, Pridatko O E, Riabukha V N
出版信息
Vopr Onkol. 1979;25(5):38-43.
PMID:462851
Abstract
In animals with Brown--Pearce carcinoma electric stimulation of the hypothalamus makes it possible to model an increased corticosterone level in blood at early stages of the tumor growth, which conditions more active development of antitumor reactions and consequently an enhanced tumor resorption. The increased level of free corticosterone seems to be essential for "triggering" and an active mode of proceeding of antitumor immune reactions.
摘要
在患有布朗-皮尔斯癌的动物中，对下丘脑进行电刺激能够模拟肿瘤生长早期血液中皮质酮水平的升高，这为抗肿瘤反应更活跃的发展创造了条件，从而促进肿瘤吸收增强。游离皮质酮水平的升高似乎对抗肿瘤免疫反应的“触发”和活跃进展模式至关重要。
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