• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

Investigations on the pharmacokinetics of nifurtimox- 35 S in the rat and dog.

作者信息

Duhm B, Maul W, Medenwald H, Patzschke K, Wegner L A

出版信息

Arzneimittelforschung. 1972 Sep;22(9):1617-24.

PMID:4630484
Abstract
摘要

相似文献

1
Investigations on the pharmacokinetics of nifurtimox- 35 S in the rat and dog.硝呋替莫-³⁵S在大鼠和犬体内的药代动力学研究。
Arzneimittelforschung. 1972 Sep;22(9):1617-24.
2
Quantitative determination of nifurtimox in body fluids of rat, dog and man.
Arzneimittelforschung. 1972 Sep;22(9):1613-7.
3
Embryotoxicity studies of nifurtimox in rats and mice and study of fertility and general reproductive performance.
Arzneimittelforschung. 1972 Sep;22(9):1603-7.
4
Absorption, distribution, biotransformation, and excretion of azidocillin, a new semi-synthetic penicillin, in mice, rats and dogs.新型半合成青霉素叠氮西林在小鼠、大鼠和犬体内的吸收、分布、生物转化及排泄
Arzneimittelforschung. 1972 Nov;22(11):1962-70.
5
[Pharmacokinetics, drug availability and clinical pharmacology of bromhexine].溴己新的药代动力学、药物可及性及临床药理学
Wien Klin Wochenschr. 1973 Sep 15;123(37):Suppl 7:1-8.
6
[Histopathological changes in the CNS of the rat after peroral administration of high doses of nifurtimox (author's transl)].经口给予大鼠高剂量硝呋替莫后中枢神经系统的组织病理学变化（作者译）
Verh Dtsch Ges Pathol. 1972;56:417-9.
7
[Pharmacokinetics of 14 C-labelled fominoben in rats and pregnant mice].[14C 标记的福尔可定在大鼠和妊娠小鼠体内的药代动力学]
Arzneimittelforschung. 1973 Feb;23:Suppl 2a:311-6.
8
[Pharmacodynamic studies after short- and long-term treatment with radioactively labelled 3-(beta-diethylamino-ethyl)-4-methyl-7-carbethoxy-2-oxo-(1,2-chromene)-hydrochloride in animal experiments].[放射性标记的3-（β-二乙氨基乙基）-4-甲基-7-乙氧羰基-2-氧代-（1,2-苯并二氢吡喃）盐酸盐在动物实验中的短期和长期治疗后的药效学研究]
Arzneimittelforschung. 1972 Aug;22(8):1242-50.
9
Metabolism of glipizide in the rat and dog and its tissue distribution in the mouse.
Arzneimittelforschung. 1973 Feb;23(2):242-7.
10
The synthesis and metabolic fate of 14 C-viminol, a new analgesic, in the rat and the dog.
Arzneimittelforschung. 1973 May;23(5):708-12.

引用本文的文献

1
Redefining the treatment of Chagas disease: a review of recent clinical and pharmacological data for a novel formulation of nifurtimox.重新定义恰加斯病的治疗：硝呋替莫新制剂近期临床和药理学数据综述
PLoS Negl Trop Dis. 2025 Feb 25;19(2):e0012849. doi: 10.1371/journal.pntd.0012849. eCollection 2025 Feb.
2
Metabolism of Nifurtimox and the Drug-Drug Interaction Potential Including its Major Metabolites.硝呋替莫代谢及包括其主要代谢物在内的药物相互作用潜力。
Curr Drug Metab. 2023;24(8):599-610. doi: 10.2174/1389200224666230817114758.
3
Structural and Mechanistic Investigation of the Unusual Metabolism of Nifurtimox.
关于硝呋替莫异常代谢的结构和机制研究。
Chem Res Toxicol. 2022 Nov 21;35(11):2037-2048. doi: 10.1021/acs.chemrestox.2c00210. Epub 2022 Oct 9.
4
Biopharmaceutical Characteristics of Nifurtimox Tablets for Age- and Body Weight-Adjusted Dosing in Patients With Chagas Disease.调整剂量用于恰加斯病患者的硝呋替莫片的生物制药特性：年龄和体重调整。
Clin Pharmacol Drug Dev. 2021 May;10(5):542-555. doi: 10.1002/cpdd.871. Epub 2020 Oct 8.
5
The Drugs of Sleeping Sickness: Their Mechanisms of Action and Resistance, and a Brief History.昏睡病的药物：其作用机制、耐药性及简史
Trop Med Infect Dis. 2020 Jan 19;5(1):14. doi: 10.3390/tropicalmed5010014.
6
Experimental and Clinical Treatment of Chagas Disease: A Review.恰加斯病的实验与临床治疗综述
Am J Trop Med Hyg. 2017 Nov;97(5):1289-1303. doi: 10.4269/ajtmh.16-0761. Epub 2017 Oct 10.
7
The distribution of nifurtimox across the healthy and trypanosome-infected murine blood-brain and blood-cerebrospinal fluid barriers.硝呋替莫在健康和感染锥虫的鼠血脑及血脑脊液屏障中的分布。
J Pharmacol Exp Ther. 2011 Feb;336(2):506-15. doi: 10.1124/jpet.110.172981. Epub 2010 Nov 5.
8
Pediatric clinical pharmacology studies in Chagas disease: focus on Argentina.恰加斯病的儿科临床药理学研究：聚焦阿根廷
Paediatr Drugs. 2009;11(1):33-7. doi: 10.2165/0148581-200911010-00012.
9
The pharmacokinetics of nifurtimox in chronic renal failure.硝呋替莫在慢性肾衰竭中的药代动力学。
Eur J Clin Pharmacol. 1992;42(6):671-3. doi: 10.1007/BF00265935.