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后代性别对黑腹果蝇无雄性基因致死表达的相对影响。

The relative influence of sex of progeny on the lethal expression of the sonless gene in Drosophila melanogaster.

作者信息

Colaianne J J, Bell A E

出版信息

Genetics. 1972 Oct;72(2):293-6. doi: 10.1093/genetics/72.2.293.

Abstract

The sex-linked maternally influenced lethal gene, sonless (snl), in D. melanogaster was shown to affect the survival of daughters as well as sons of snl/snl mothers but to a lesser degree. Interaction studies of sonless with the sex altering mutants transformer (tra) and doublesex (dsx) revealed that any alteration toward increased masculinity of progeny from snl/snl females reduced their zygotic viability, independent of snl dosage or Y chromosome presence or absence. Possible implications of these results are discussed and the original gene action hypothesis for snl is extended to incorporate these new findings.-Sonless is non-allelic but closely linked to rudimentary (r) and fused (fu), two mutants with similar sex-ratio patterns.

摘要

在黑腹果蝇中,性连锁的母性影响致死基因“无雄性后代”(sonless,snl)被证明会影响snl/snl母亲的女儿以及儿子的存活,但影响程度较小。对无雄性后代基因与性别改变突变体“变异性别”(transformer,tra)和“双性”(doublesex,dsx)的相互作用研究表明,snl/snl雌性后代向雄性化增加的任何改变都会降低其合子活力,这与snl剂量或Y染色体的存在与否无关。讨论了这些结果可能的意义,并扩展了关于snl的原始基因作用假说以纳入这些新发现。无雄性后代基因与“残翅”(rudimentary,r)和“融合翅脉”(fused,fu)这两个具有相似性别比例模式的突变体是非等位基因,但紧密连锁。

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