Chan J C
Va Med. 1979 May;106(5):384-90.
The discovery that the kidney is the site of production of calcitriol clarifies our understanding of calcium metabolic disorders in chronic renal failure and carries with it clinical implications in the treatment of renal rickets. The author presents data on the action of calcium and reviews the therapeutic effects on uremic osteodystrophy in children of calcitriol and its analogue.
肾脏是骨化三醇生成部位这一发现,阐明了我们对慢性肾衰竭钙代谢紊乱的理解,并对肾性佝偻病的治疗具有临床意义。作者展示了关于钙作用的数据,并综述了骨化三醇及其类似物对儿童尿毒症性骨营养不良的治疗效果。