蛋白质缺乏的兔子对葡萄球菌菌血症的反应。

Bhuyan U N, Ramalingaswami V

Am J Pathol. 1972 Nov;69(2):359-68.

Staphylococcal bacteremia was induced in two groups of rabbits that were pairfed high protein and protein deficient diets. Marked deviations in response were observed as a result of protein deficiency: a) blood clearance of S aureus was delayed; b) persistence and multiplication of bacteria in blood and tissues were pronounced; c) neutrophilic response was poor and transitory; d) mortality was very high and occurred very early and e) focal necrotizing lesions, rather than well-formed abscesses, were found in organs.

在两组分别以高蛋白和蛋白质缺乏饮食进行配对喂养的兔子中诱发葡萄球菌菌血症。观察到由于蛋白质缺乏导致的明显反应偏差：a）金黄色葡萄球菌的血液清除延迟；b）细菌在血液和组织中的持续存在和增殖明显；c）嗜中性粒细胞反应不佳且短暂；d）死亡率非常高且发生得非常早；e）在器官中发现的是局灶性坏死病变，而不是形成良好的脓肿。