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导致小于胎龄儿的妊娠中的血小板寿命。

Platelet life span in pregnancies resulting in small-for-gestational age infants.

作者信息

Wallenburg H C, van Kessel P H

出版信息

Am J Obstet Gynecol. 1979 Aug 1;134(7):739-42. doi: 10.1016/0002-9378(79)90939-6.

DOI:10.1016/0002-9378(79)90939-6
PMID:463973
Abstract

Platelet number and life span were determined in the last trimester of pregnancy in 22 women who were delivered of small-for-gestational age (SGA) infants and in 21 women with infants having normal birth weights. Platelet life span was determined by means of a nonradioisotopic method involving the use of acetylsalicylic acid. Mean platelet life span was 7.2 days in women with SGA infants, which is significantly shorter than the 9.2 days found in the control group. The mean platelet count in the SGA group was 235 x 10(9)/L, whereas in the control group it was 208 x 10(9)/L. These data indicate the existence of a compensated thrombocytolytic state in pregnancies with insufficient fetal growth. This could be explained by an increased platelet consumption in the uteroplacental arterial bed.

摘要

对22名分娩出小于胎龄(SGA)婴儿的女性和21名婴儿出生体重正常的女性在妊娠晚期测定了血小板数量和寿命。血小板寿命通过一种涉及使用乙酰水杨酸的非放射性方法测定。SGA婴儿母亲的平均血小板寿命为7.2天,明显短于对照组的9.2天。SGA组的平均血小板计数为235×10⁹/L,而对照组为208×10⁹/L。这些数据表明,在胎儿生长不足的妊娠中存在代偿性血小板溶解状态。这可能是由于子宫胎盘动脉床中血小板消耗增加所致。

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