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对拟暗果蝇中sal基因座的研究。II. sal带纹模式的调控方式。

Studies on the sal locus in Drosophila pseudoobscura. II. Modes of regulation of the sal banding pattern.

作者信息

Gersh E S

出版信息

Genetics. 1972 Nov;72(3):531-6. doi: 10.1093/genetics/72.3.531.

Abstract

From a consideration of genetic and chromosomal alterations which affect the banding pattern of a specific salivary chromosome region, it is concluded that (1) a regulator locus, sal, is closely linked with the region in question but separated from it spatially by a few bands; (2) either mutation of the sal locus or transfer of the region to a heterochromatic region affects the banding pattern similarly; and (3) the change probably consists of a compaction of DNA and a concomitant inactivation of genetic loci.

摘要

通过对影响特定唾液腺染色体区域带型的遗传和染色体改变的研究得出以下结论

(1)一个调控位点sal与相关区域紧密连锁,但在空间上与之相隔几条带;(2)sal位点的突变或该区域转移到异染色质区域对带型产生相似的影响;(3)这种变化可能包括DNA的压缩以及伴随的基因位点失活。

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