Gersh E S
Genetics. 1972 Nov;72(3):531-6. doi: 10.1093/genetics/72.3.531.
From a consideration of genetic and chromosomal alterations which affect the banding pattern of a specific salivary chromosome region, it is concluded that (1) a regulator locus, sal, is closely linked with the region in question but separated from it spatially by a few bands; (2) either mutation of the sal locus or transfer of the region to a heterochromatic region affects the banding pattern similarly; and (3) the change probably consists of a compaction of DNA and a concomitant inactivation of genetic loci.
(1)一个调控位点sal与相关区域紧密连锁,但在空间上与之相隔几条带;(2)sal位点的突变或该区域转移到异染色质区域对带型产生相似的影响;(3)这种变化可能包括DNA的压缩以及伴随的基因位点失活。