Simón J, Mendizábal S, Zamora I, Roques V, Orive B
An Esp Pediatr. 1979 Apr;12(4):283-96.
A retrospective study of 35 newborn with acute renal failure is presented. The main causes of renal failure were neonatal hypoxia by asfixia or hemorrhagic shock (eight), congenital malformations (two) and hypertonic dehydration (25). Mortality rate was 22% including two neonates with severe congenital malformations. Sepsis was considered as the main complicating factor and often as inducer of renal failure. It was present on 55% of cases and on 75% of the deceased newborn. Cerebral injury was frequent but a follow-up study is necessary to establish the rate of neurologic sequelae. Early diagnosis and treatment of renal failure will decrease complications with improvement in prognosis. Etiological analysis of neonatal renal failure shows the need of a better health education of people and also medical control of pregnancy and perinatal period.
本文对35例急性肾衰竭新生儿进行了回顾性研究。肾衰竭的主要病因是窒息或失血性休克导致的新生儿缺氧（8例）、先天性畸形（2例）和高渗性脱水（25例）。死亡率为22%，其中包括2例患有严重先天性畸形的新生儿。脓毒症被认为是主要的并发症因素，且常常是肾衰竭的诱因。它出现在55%的病例中，在死亡新生儿中占75%。脑损伤很常见，但需要进行随访研究以确定神经后遗症的发生率。肾衰竭的早期诊断和治疗将减少并发症并改善预后。新生儿肾衰竭的病因分析表明，需要对人群进行更好的健康教育，同时加强孕期和围产期的医疗管理。
