Von Hartitzsch B, Hoenich N A, Leigh R J, Wilkinson R, Frost T H, Weddel A, Posen G A
Br Med J. 1972 Dec 30;4(5843):757-9. doi: 10.1136/bmj.4.5843.757.
THREE PATIENTS WITH LITHIUM TOXICITY ARE REPORTED, TWO OF WHOM WERE EXPOSED TO TOXIC LITHIUM LEVELS FOR A PROLONGED PERIOD: both survived with permanent damage to basal ganglia and cerebellar connexions despite effective lowering of lithium levels by haemodialysis. Data obtained during dialysis treatment show prolonged haemodialysis to be the treatment of choice. If facilities for haemodialysis are not available or the patient presents with toxic lithium levels and minimal symptoms peritoneal dialysis will effectively lower serum lithium levels, but more slowly than haemodialysis.
报告了3例锂中毒患者，其中2例长期暴露于中毒性锂水平：尽管通过血液透析有效降低了锂水平，但两人均存活下来，基底神经节和小脑连接受到永久性损伤。透析治疗期间获得的数据表明，延长血液透析是首选治疗方法。如果没有血液透析设备，或者患者出现中毒性锂水平且症状轻微，腹膜透析将有效降低血清锂水平，但比血液透析慢。
