Bake B, Bjure J, Kasalichý J, Nachemson A
Thorax. 1972 Nov;27(6):703-12. doi: 10.1136/thx.27.6.703.
Regional lung function using xenon-133 was studied in 45 seated patients aged 11 to 78 years with untreated idiopathic scoliosis and angulation of curvature between 10 and 190°. Perfusion distribution was assessed by intravenous bolus injection of Xe and distribution of ventilation to volume ratios by washouts after inhalation and intravenous injection. No consistent differences between the lungs on the convex and concave sides of the curvature were found. The lung bases were found to be more severely affected than the apices, perfusion and ventilation being progressively reduced with increasing deformity. There was evidence of inhomogeneity within regions and it is suggested that in younger patients the ventilation and perfusion within regions are better matched than in older patients.
对45例年龄在11至78岁之间、未经治疗的特发性脊柱侧弯且弯曲角度在10°至190°之间的坐位患者，使用氙-133研究了区域肺功能。通过静脉推注氙评估灌注分布，并通过吸入和静脉注射后的冲洗评估通气与容积比的分布。未发现弯曲凸侧和凹侧肺部之间存在一致差异。发现肺底部比肺尖受影响更严重，随着畸形增加，灌注和通气逐渐减少。有证据表明区域内存在不均匀性，提示年轻患者区域内的通气和灌注比老年患者更匹配。
