Volterrani P, Peradotto F
Arch Sci Med (Torino). 1979 Jan-Mar;136(1):37-44.
218 patients examined for localized cancer of the extremities (50% benign, 50% malignant) are reported. The incidence is considered by sex and age. Demolition surgery was carried out in 35 patients and 27 locoregional treatment with antiblastics and radioactive isotopes was employed. Conservative surgery was used in 158. Operative mortality was less than 1% (2 cases out of 218) and did not reach 6% if amputations and disarticulations alone are considered. There were no deaths in cases submitted to radiochemotherapy and inguinocrural hymphadenectomy. The series includes a 15-years survival for giant-cell tumour of the femur treated with radioactive microsphores, an 11-years survival for a popliteal melanoma submitted to radiocolloid infiltration, a 9-year survival for femoral osteosarcoma for which hip disarticulation was carried out and a 4-year survival for a recurrent rhabdomyosarcoma of the hip operated by hemipelvectomy.
报告了218例接受四肢局限性癌症检查的患者(50%为良性,50%为恶性)。按性别和年龄对发病率进行了分析。35例患者接受了截肢手术,27例采用抗代谢药和放射性同位素进行局部区域治疗。158例采用了保守手术。手术死亡率低于1%(218例中有2例),若仅考虑截肢和关节离断术,死亡率未达到6%。接受放化疗和腹股沟股淋巴结切除术的患者无死亡病例。该系列包括1例采用放射性微球治疗的股骨巨细胞瘤存活15年的病例、1例接受放射性胶体浸润的腘窝黑色素瘤存活11年的病例、1例接受髋关节离断术的股骨骨肉瘤存活9年的病例以及1例接受半骨盆切除术的复发性臀部横纹肌肉瘤存活4年的病例。