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拉伸犬上腔静脉-右心房连接处对右心房感受器的影响。

The effect of stretching the superior vena caval-right atrial junction on right atrial receptors in the dog.

作者信息

Kappagoda C T, Linden R J, Snow H M

出版信息

J Physiol. 1972 Dec;227(3):875-87. doi: 10.1113/jphysiol.1972.sp010063.

DOI:10.1113/jphysiol.1972.sp010063
PMID:4650940
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1331291/
Abstract
  1. Action potentials were recorded from fibres in the right cervical vagus, the receptor endings of which were localized to the endocardial surface of the superior vena caval-right atrial junction.2. Stretching the junction between the superior vena cava and the right atrium without obstructing venous return caused an increase in the discharge of these fibres. This increase in impulse frequency was similar to that caused by small changes in mean right atrial pressure (range 0-13.5 cm H(2)O).3. This evidence supports the earlier suggestion that stimulation of the right atrial receptors by stretching the superior vena caval-right atrial junction causes a reflex increase in heart rate.
摘要

  1. 从右侧颈迷走神经的纤维记录动作电位，其感受器末梢定位于上腔静脉-右心房交界处的心内膜表面。

  2. 在不阻碍静脉回流的情况下拉伸上腔静脉与右心房之间的交界处，会导致这些纤维的放电增加。这种冲动频率的增加与平均右心房压力的微小变化（范围为0 - 13.5厘米水柱）所引起的增加相似。

  3. 这一证据支持了早期的推测，即通过拉伸上腔静脉-右心房交界处来刺激右心房感受器会导致心率反射性增加。

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本文引用的文献

1
CARDIAC RECEPTORS IN THE DOG, WITH PARTICULAR REFERENCE TO TWO TYPES OF AFFERENT ENDING IN THE VENTRICULAR WALL.犬心脏的感受器，特别涉及心室壁中的两种传入末梢类型。
J Physiol. 1964 Nov;174(3):323-39. doi: 10.1113/jphysiol.1964.sp007490.
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STUDIES ON THE NERVE ENDINGS IN THE HEART.心脏神经末梢的研究
Am J Anat. 1964 Sep;115:217-33. doi: 10.1002/aja.1001150203.
3
The location of atrial receptors in the dog: a physiological and histological study.犬心房感受器的定位：一项生理学与组织学研究。
J Physiol. 1957 Apr 3;136(1):174-97. doi: 10.1113/jphysiol.1957.sp005750.
4
The possible role of cardiac atrial stretch receptors in the induction of changes in urine flow.心脏心房牵张感受器在诱导尿流变化中的可能作用。
J Physiol. 1956 Mar 28;131(3):572-85. doi: 10.1113/jphysiol.1956.sp005483.
5
A study of right and left atrial receptors.一项关于左右心房感受器的研究。
J Physiol. 1953 Jun 29;120(4):596-610. doi: 10.1113/jphysiol.1953.sp004920.
6
An anaesthetic machine for dogs.一种用于犬类的麻醉机。
J Physiol. 1967 Jul;191(2):61P-62P.
7
The measurement of pH, PCO2 and PO2 in blood.血液中pH值、二氧化碳分压和氧分压的测量。
J Physiol. 1967 Jul;191(2):59P-60P.
8
Further evidence for right atrial receptors affecting heart rate.右心房受体影响心率的进一步证据。
J Physiol. 1970 Sep;210(2):132P-133P.
9
The effect of distending the junction between the superior vena cava and the right atrium in the dog.扩张犬上腔静脉与右心房连接处的影响。
J Physiol. 1970 Jun;208(2):59P-60P.
10
A reflex increase in heart rate from distension of the junction between the superior vena cava and the right atrium.上腔静脉与右心房交界处扩张引起的心率反射性增加。
J Physiol. 1972 Jan;220(1):177-97. doi: 10.1113/jphysiol.1972.sp009700.