Suarez L D, Sciandro E E, Llera J J, Perosio A M
Br Heart J. 1979 Jun;41(6):702-8. doi: 10.1136/hrt.41.6.702.
Two patients with severe primary pulmonary hypertension, who are alive 38 and 27 years after the onset of the disease, were closely followed by the authors for 24 years. No previous report of such a long course has been found. Despite pulmonary artery pressures at systemic level, effort syncope disappeared and there were long intervals without symptoms during which the 2 patients were able to take part in physical activity with minimal discomfort. Severe primary pulmonary hypertension should not always be considered a malignant disease.
两名重度原发性肺动脉高压患者，在发病后分别存活了38年和27年，作者对其进行了24年的密切随访。此前尚未发现有如此漫长病程的报道。尽管肺动脉压力处于体循环水平，但劳力性晕厥消失，且在很长一段时间内无症状，在此期间这两名患者能够以最小的不适参与体育活动。重度原发性肺动脉高压不应总是被视为恶性疾病。
