Jouppila P, Tapanainen J, Huhtaniemi I
Br J Obstet Gynaecol. 1979 May;86(5):343-9. doi: 10.1111/j.1471-0528.1979.tb10608.x.
The prognostic value of maternal plasma human chorionic gonadotrophin (hCG) determinations, measured by a specific beta-subunit radioimmunoassay, was studied in 188 patients with bleeding between 6 and 20 weeks gestation. The patients were arranged into different subgroups according to ultrasound findings as well as clinical and histopathological evidence. In threatened abortion with successful outcome (50 per cent of all patients studied), the weekly mean hCG values were normal or even slightly elevated. In patients with a blighted ovum, the first hCG level measured was in the normal range in 34 per cent of the patients. In patients who aborted embryo with former life signs hCG values were generally normal before the abortion. The hCG levels were usually low in patients with incomplete abortion and ectopic pregnancy. An initially subnormal level of hCG was associated with a poor outcome of pregnancy in 92 per cent of patients. If the first hCG level was within the normal range the outcome of pregnancy was favourable in 79 per cent of patients.
采用特异性β亚基放射免疫分析法测定了188例妊娠6至20周有阴道出血的患者母血人绒毛膜促性腺激素（hCG）水平，并研究其预后价值。根据超声检查结果以及临床和组织病理学证据将患者分为不同亚组。在结局良好的先兆流产患者中（占所有研究患者的50%），每周hCG均值正常甚至略有升高。在空孕囊患者中，34%的患者首次测得的hCG水平在正常范围内。在有过胚胎存活迹象但胚胎流产的患者中，流产前hCG值通常正常。不全流产和异位妊娠患者的hCG水平通常较低。92%的患者hCG初始水平低于正常与妊娠不良结局相关。若首次hCG水平在正常范围内，79%的患者妊娠结局良好。
