Dabrowska J, Szafrańska-Kosmal A
Acta Neurobiol Exp (Wars). 1972;32(4):817-34.
The effects of partial bilateral lesions situated in the prefrontal region on go-no go differentiation with symmetrical reinforcement were investigated in dogs. Bilateral removals of proreal gyri and medial cortical surface involving pregenual, genual, precruciatal (XM), subcallosal or medial subproreal areas did not impair performance of this test. Very small cortical lesions of proreal areas located under presylvian fissure impaired transiently the differentiation. Removals of the orbital gyri to the presylvian fissure caused severe and long lasting impairment of this differentiation. It was concluded that the orbital areas situated on the lateral aspect of the hemisphere in dogs was responsible for correct performance of go-no go symmetrically reinforced differentiation task.
在犬类中研究了位于前额叶区域的部分双侧损伤对具有对称强化的去/不去分化的影响。双侧切除额前回和内侧皮质表面，包括膝前、膝部、前十字（XM）、胼胝体下或内侧额前下区域，并不损害该测试的表现。位于ylvian前裂下方的额前区域的非常小的皮质损伤会暂时损害分化。切除至ylvian前裂的眶回会导致这种分化严重且持久的损害。得出的结论是，犬类大脑半球外侧的眶区负责去/不去对称强化分化任务的正确执行。
