Leach R D, Eykyn S J, Phillips I, Corrin B, Taylor E A
Br Med J. 1979 Jul 7;2(6181):5-7. doi: 10.1136/bmj.2.6181.5.
Fifty-two patients with axillary abscesses were seen during two years. Staphylococcus aureus was isolated from 34, anaerobic bacteria from 12, and skin flora from five; in one case the pus was sterile. Seven patients with hidradenitis suppurativa had recurrent infection with abscess formation, which was bilateral in three. Anaerobes were isolated in five of these cases and skin flora alone in two. Anaerobes are secondary invaders in this condition, and histological examination shows that the primary abnormality is obstruction of pilosebaceous follicles and apocrine glands, associated with keratin plugging of the follicles. Chemotherapy offers little hope of cure, although metronidazole removes the offensive smell of the discharge. Radical surgery is usually indicated.
在两年期间共诊治了52例腋窝脓肿患者。从34例中分离出金黄色葡萄球菌,12例中分离出厌氧菌,5例中分离出皮肤菌群;1例脓液无菌。7例化脓性汗腺炎患者反复感染并形成脓肿,其中3例为双侧。这些病例中有5例分离出厌氧菌,2例仅分离出皮肤菌群。厌氧菌在这种情况下是继发性入侵者,组织学检查表明主要异常是毛囊和顶泌汗腺阻塞,伴有毛囊角质栓塞。化疗治愈的希望渺茫,尽管甲硝唑可消除分泌物的恶臭味。通常需要进行根治性手术。