Fraunfelder F T, Hanna C
Am J Ophthalmol. 1975 Feb;79(2):262-70. doi: 10.1016/0002-9394(75)90080-x.
Asymptomatic peripheral subconjunctival and episcleral clear, round globules, 30 to 50 mu in diameter, were found in more than 50% of patients over 50 years of age. This entity occurred in two basic patterns, adjacent to deep conjunctival or episcleral blood vessels or less commonly in isolated patches. These globules increased linearly with age, were more common in women and blacks, with a peak incidence in blacks during the fourth, and in whites, the sixth decade. Histologically, the globules were connective tissue fat cells identical to those found in orbital fat. This entity is not related to obesity, but has a clear relationship to increasing age. The clinical importance of these cells is unknown.
在50岁以上的患者中，超过50%发现有无症状的周边结膜下和巩膜表层透明、圆形小球，直径为30至50微米。该病变有两种基本形态，与深层结膜或巩膜血管相邻，或较少见地呈孤立斑片状。这些小球随年龄呈线性增加，在女性和黑人中更常见，黑人在第四个十年发病率最高，白人在第六个十年发病率最高。组织学上，这些小球是与眼眶脂肪中发现的相同的结缔组织脂肪细胞。该病变与肥胖无关，但与年龄增长有明确关系。这些细胞的临床意义尚不清楚。
