Thoa N B, Eichelman B, Richardson J S, Jacobowitz D
Science. 1972 Oct 6;178(4056):75-7. doi: 10.1126/science.178.4056.75.
A significant increase in shock-induced aggression occurs in the rat 4 days after an intraventricular injection of 90 micrograms of 6-hydroxydopa. Both fluorescent histology and biochemical assay demonstrate that brain norepinephrine is reduced by 90 micrograms of 6-hydroxydopa, while brain dopamine remains unaltered. This suggests that one form of aggressive behavior (shock-induced aggression) is modulated through a central noradrenergic system.
脑室内注射90微克6-羟基多巴胺4天后，大鼠因电击诱发的攻击性显著增加。荧光组织学和生化分析均表明，90微克6-羟基多巴胺可使脑内去甲肾上腺素减少，而脑内多巴胺则无变化。这表明一种攻击行为（电击诱发的攻击）是通过中枢去甲肾上腺素能系统调节的。
