Mutafchiev D A
Eksp Med Morfol. 1979;18(2):72-6.
The authors administered thyreotropic hormone in a dose of 2 international units/kg of body weight on lactating rabbits intramuscularly. Concentrations of iron and iron-binding capacity in milk were examined at different days (from 7 to 21 days after delivery) of the lactation period of the animals. The obtained results suggested an inhibiting effect of thyreotropin on the content of iron and iron-binding capacity in milk after the first day of treatment. Later there was a gradual recovery of values almost to the initial values of the control day, which indicated transitory and comparatively quickly disappearing hormonal effect. The presumed mechanisms for this effect of thyreotropic hormone were discussed.
作者给哺乳期家兔肌肉注射促甲状腺激素,剂量为2国际单位/千克体重。在动物哺乳期的不同天数(分娩后7至21天)检测了乳汁中铁和铁结合能力的浓度。所得结果表明,治疗第一天后促甲状腺素对乳汁中铁含量和铁结合能力有抑制作用。之后这些值逐渐恢复,几乎达到对照日的初始值,这表明激素作用是暂时的且相对较快消失。文中讨论了促甲状腺激素产生这种作用的推测机制。