DeSa D J
J Clin Pathol. 1972 Dec;25(12):1063-70. doi: 10.1136/jcp.25.12.1063.
The macroscopic and microscopic findings in 12 cases of stenosis and/or atresia of the jejunum and ileum are presented. There was considerable uniformity within the series with overlapping of cases of atresia, stenosis, and gut infarction. An analysis of associated lesions in cases coming to necropsy suggests that the infants were suffering from shock. In nine out of the 12 cases there was evidence of intrapartum asphyxia and in eight cases evidence of retardation of intrauterine growth. It is argued that, since many of the associated complications of pregnancy are known to be of importance in the aetiology of gut infarction in the neonatal period, they are likely to be of aetiological significance in the development of atresia and stenosis of the gut. A review of perinatal deaths shows that gut ischaemia of varying degrees of severity is a common finding at necropsy, being noted in 19 out of 56 cases studied. It is suggested that stenosis and atresia are sequelae of previous gut ischaemia.
本文呈现了12例空肠和回肠狭窄及/或闭锁的宏观和微观检查结果。该系列病例表现出相当的一致性，闭锁、狭窄和肠梗死病例存在重叠。对尸检病例相关病变的分析表明，这些婴儿患有休克。12例中有9例有产时窒息的证据，8例有宫内生长迟缓的证据。有人认为，鉴于已知许多妊娠相关并发症在新生儿期肠道梗死的病因中具有重要意义，它们在肠道闭锁和狭窄的发生中可能也具有病因学意义。对围产期死亡病例的回顾显示，不同严重程度的肠道缺血在尸检中是常见发现，在所研究的56例中有19例出现。有人提出，狭窄和闭锁是先前肠道缺血的后遗症。
