[Microscopic, micro-chemical and fluorescent optical findings in endometrium with a copper-T intrauterine device in situ (author's transl)].

The uteri of ten patients who wore a copper-T for several months up to two years were examined immediately following hysterectomy by conventional microscopic techniques, fluorescent optical techniques after Acridin-Orange-Fluorochromization and by histo-chemical techniques for copper. With none of these methods changes in the endometrium could be found which explained the effect of the copper-T to inhibit implantation. Since practically any morphological change from the normal was absent it is suggested that the inhibiting effect on pregnancy of the copper intra-uterine devices is due to biochemical changes of the intra-uterine environment.