日本人群唾液遗传标记系统的频率及其在法医学中的应用。

Frequencies of salivary genetic marker systems in the Japanese population and their application to forensic medicine.

作者信息

Ikemoto S, Tomita K, Minaguchi K, Suzuki K

出版信息

Forensic Sci Int. 1979 Jul-Aug;14(1):41-7. doi: 10.1016/0379-0738(79)90153-1.

Abstract

Seven salivary polymorphic systems were studied using whole and parotid saliva from random Japanese individuals. The gene frequencies obtained were: Pa+ = 0.212, Pb1 = 1.000, Pb2 = 0, Pr1 = 0.763, Pr2 = 0.237, Db+ = 0.051, Pm+ = 0.409, Ph+ = 0.026 and Amy1v = 0.013, respectively. Based on these gene frequencies, the chances for exclusion of falsely alleged fathers were calculated. The chance of exclusion on the basis of five salivary polymorphic systems was 0.305. The combined chance of exclusion utilizing only blood, serum and red-cell enzyme polymorphic systems among the Japanese population was 0.919; however, by applying salivary polymorphic systems to the calculation, the total exclusion rose to 0.944.

摘要

使用来自随机选取的日本个体的全唾液和腮腺唾液，研究了七个唾液多态性系统。获得的基因频率分别为：Pa+ = 0.212、Pb1 = 1.000、Pb2 = 0、Pr1 = 0.763、Pr2 = 0.237、Db+ = 0.051、Pm+ = 0.409、Ph+ = 0.026以及Amy1v = 0.013。基于这些基因频率，计算了排除错误声称父亲的几率。基于五个唾液多态性系统的排除几率为0.305。在日本人群中，仅利用血液、血清和红细胞酶多态性系统的综合排除几率为0.919；然而，通过将唾液多态性系统应用于计算，总排除率升至0.944。