在小鼠对绵羊红细胞的反应过程中，与介导迟发型超敏反应的细胞表达的放射抗性相比，诱导具有高放射敏感性。
High radiosensitivity of induction in contrast to radioresistance of expression of cells mediating delayed-type hypersensitivity during response to sheep red blood cells in mice.
作者信息
Marchal G, Milon G, Hurtrel B
出版信息
Immunology. 1979 May;37(1):273-8.
The delayed-type hypersensitivity DTH) reaction observed in mice primed i.v. with low doses of sheep red blood cells was greatly decreased when mice were irradiated with 300 rad before priming. An estimation of the radiosensitivity of DTH-mediating cells (DTH-C) was performed using a titration assay after local adoptive transfer of these cells mixed with antigen into the footpad of unprimed mice. A high radiosensitivity of the induction of DTH-C was observed with a D37 of approximately 50 rad. In contrast, the expression of DTH-C appeared radioresistant, as the D37 was approximately 2000 rad.
用低剂量绵羊红细胞经静脉注射致敏的小鼠所观察到的迟发型超敏反应（DTH），在致敏前用300拉德照射小鼠时会大大降低。在用这些细胞与抗原混合后通过局部过继转移至未致敏小鼠的足垫后，利用滴定试验对介导DTH的细胞（DTH-C）的放射敏感性进行了评估。观察到诱导DTH-C具有较高的放射敏感性，D37约为50拉德。相比之下，DTH-C的表达似乎具有放射抗性，因为D37约为2000拉德。
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