Price N M
Int J Dermatol. 1979 Jun;18(5):390-3. doi: 10.1111/ijd.1979.18.5.390.
The topical application of mechlorethamine is associated with a high incidence of irritant contact dermatitis. An attempt was made to avoid this complication by the use of a topical tolerogenic schedule. Seven of ten patients developed contact dermatitis to the medication after they had completed the schedule, The use of this medication in its present form is unlikely to be practical value in the treatment of psoriasis.
氮芥的局部应用与刺激性接触性皮炎的高发病率相关。曾尝试通过采用局部耐受方案来避免这种并发症。十名患者中有七名在完成该方案后出现了对该药物的接触性皮炎。以其目前的形式使用这种药物在银屑病治疗中不太可能具有实用价值。
