Fidler M
Br Med J. 1973 Feb 10;1(5849):341-3. doi: 10.1136/bmj.1.5849.341.
The notes and radiographs of 19 patients who had pathological fractures of long bones due to secondary neoplastic deposits were reviewed. Involvement of over half of the cortex is recommended as an indication for prophylactic internal fixation to prevent the development of a pathological fracture. Eight patients were treated successfully in this way. A notable secondary effect of prophylactic internal fixation was the considerable reduction in pain at the site of the lesion.
回顾了19例因继发性肿瘤沉积导致长骨病理性骨折患者的病历和X光片。建议当超过一半的皮质骨受累时，作为预防性内固定的指征，以防止病理性骨折的发生。8例患者通过这种方式得到成功治疗。预防性内固定的一个显著的次要效果是病变部位疼痛明显减轻。
