Crook T
J Am Geriatr Soc. 1979 Oct;27(10):476-7. doi: 10.1111/j.1532-5415.1979.tb01731.x.
CNS stimulants such as methylphenidate and pentylenetetrazol are currently prescribed for the treatment of aged persons with symptoms of senility. A review of clinical studies conducted with these compounds indicates that firm evidence of efficacy is lacking. Because of the risks associated with high doses of such stimulants in the aged, it would seem that these compounds are of limited utility in geriatric psychiatry.
中枢神经系统兴奋剂，如哌醋甲酯和戊四氮，目前被用于治疗有衰老症状的老年人。对使用这些化合物进行的临床研究的综述表明，缺乏其疗效的确切证据。鉴于高剂量此类兴奋剂对老年人存在风险，这些化合物在老年精神病学中的效用似乎有限。
