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[早期反复流产与核型。对80对连续夫妇的细胞遗传学研究(作者译)]

[Early repeated abortions and karyotypes. A cytogenic study of 80 consecutive couples (author's transl)].

作者信息

Pescia G, Jotterand M, Gaide A C

出版信息

J Gynecol Obstet Biol Reprod (Paris). 1979 Jan-Feb;8(1):35-8.

PMID:469198
Abstract

The authors report the results of a cystogenic study of 80 couples (160 individuals) who had early repeated abortions. A significant karyotype abnormality was found in 5 per cent of the partners. Where a translocation of 2 heterological chromosomes is found in a partner, the recommendations is to attempt an antenatal diagnostic. Once a couple have had 2 abortions karyotype investigation is absolutely indicated.

摘要

作者报告了对80对(160人)有早期反复流产经历的夫妇进行的致囊肿性研究结果。在5%的伴侣中发现了明显的核型异常。如果在一方伴侣中发现两条异源染色体发生易位,建议尝试进行产前诊断。一旦一对夫妇经历了两次流产,绝对需要进行核型调查。

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