Pescia G, Jotterand M, Gaide A C
J Gynecol Obstet Biol Reprod (Paris). 1979 Jan-Feb;8(1):35-8.
The authors report the results of a cystogenic study of 80 couples (160 individuals) who had early repeated abortions. A significant karyotype abnormality was found in 5 per cent of the partners. Where a translocation of 2 heterological chromosomes is found in a partner, the recommendations is to attempt an antenatal diagnostic. Once a couple have had 2 abortions karyotype investigation is absolutely indicated.
作者报告了对80对(160人)有早期反复流产经历的夫妇进行的致囊肿性研究结果。在5%的伴侣中发现了明显的核型异常。如果在一方伴侣中发现两条异源染色体发生易位,建议尝试进行产前诊断。一旦一对夫妇经历了两次流产,绝对需要进行核型调查。