Rary J M, Cummings D K, Jones H W, Rock J A
J Hered. 1979 Jan-Feb;70(1):78-80. doi: 10.1093/oxfordjournals.jhered.a109197.
We have presented two cases strongly suporting a Y chromosome short-arm location for the H-Y antigen gene. The first case was HY antigen-positive with an isochromosome for the short arm of the Y with no long arm of the Y being present. The other case was H-Y antigen-negative in fibroblasts from an individual with a 46,X,i(Yq) karyotype with no short arm of the Y present. The two cases presented also confirmed previous reports that the testicular forming gene is also located on the short arm of chromosome Y.
我们展示了两个有力支持H-Y抗原基因位于Y染色体短臂的病例。第一个病例中，H-Y抗原呈阳性，存在Y染色体短臂的等臂染色体，而不存在Y染色体长臂。另一个病例中，对于一个核型为46,X,i(Yq)且不存在Y染色体短臂的个体，其成纤维细胞中的H-Y抗原呈阴性。所展示的这两个病例也证实了先前的报道，即睾丸形成基因也位于Y染色体短臂上。
