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羊膜移植治疗遗传性出血性毛细血管扩张症所致严重鼻出血

Amniotic graft in the management of severe epistaxis due to hereditary haemorrhagic telangiectasia.

作者信息

Laurian N, Kalmanovitch M, Shimberg R

出版信息

J Laryngol Otol. 1979 Jun;93(6):589-95. doi: 10.1017/s0022215100087442.

DOI:10.1017/s0022215100087442
PMID:469391
Abstract

In selected cases of Hereditary Haemorrhagic Telangiectesia with severe, life-threatening epistaxis, a new surgical procedure has been performed. It consists of a thorough, near total excision of the diseased nasal mucosa and its replacement by an amniotic memebrane graft. The surgical details dealing with preparation of the amniotic graft are described. Surgery has been performed by this technique in six cases. During 9 to 30 min months of follow-up, no nasal bleeding has occurred and the haemoglobin level has remained normal. The aminiotic membrane has served as an adequate grafting material for the lining of the nasal chambers.

摘要

在遗传性出血性毛细血管扩张症的某些严重、危及生命的鼻出血病例中,已实施了一种新的外科手术。该手术包括彻底、近乎完全切除患病的鼻黏膜,并用羊膜移植片进行替代。文中描述了处理羊膜移植片制备的手术细节。已用此技术对6例患者实施了手术。在9至30个月的随访期间,未发生鼻出血,血红蛋白水平保持正常。羊膜已作为鼻腔内衬的一种合适移植材料。

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Amniotic graft in the management of severe epistaxis due to hereditary haemorrhagic telangiectasia.羊膜移植治疗遗传性出血性毛细血管扩张症所致严重鼻出血
J Laryngol Otol. 1979 Jun;93(6):589-95. doi: 10.1017/s0022215100087442.
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引用本文的文献

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Amniotic membrane in oral and maxillofacial surgery.口腔颌面外科中的羊膜
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Biological materials used in reconstruction of the ear.用于耳部重建的生物材料。
J R Soc Med. 1983 Jan;76(1):82. doi: 10.1177/014107688307600120.