通过给母亲服用苯巴比妥来诱导人胎儿肝脏和胎盘的药物代谢的尝试。 - Suppr

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超能文献

Attempts to induce drug metabolism in human fetal liver and placenta by the administration of phenobarbital to mothers.

作者信息

Pelkonen O, Jouppila P, Kärki N T

出版信息

Arch Int Pharmacodyn Ther. 1973 Apr;202(2):288-97.

PMID:4694366

Abstract

摘要

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Attempts to induce drug metabolism in human fetal liver and placenta by the administration of phenobarbital to mothers.通过给母亲服用苯巴比妥来诱导人胎儿肝脏和胎盘的药物代谢的尝试。

Arch Int Pharmacodyn Ther. 1973 Apr;202(2):288-97.

Drug metabolism in the human fetal liver. Relationship to fetal age.人类胎儿肝脏中的药物代谢。与胎龄的关系。

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Effect of maternal cigarette smoking on 3,4-benzpyrene and N-methylaniline metabolism in human fetal liver and placenta.母亲吸烟对人胎儿肝脏和胎盘内3,4-苯并芘及N-甲基苯胺代谢的影响。

Toxicol Appl Pharmacol. 1972 Nov;23(3):399-407. doi: 10.1016/0041-008x(72)90042-7.

Perinatal drug metabolism and morphological changes in the hepatocytes of normal and phenobarbital-treated guinea pigs.正常和苯巴比妥处理的豚鼠围产期药物代谢及肝细胞形态学变化

J Pharmacol Exp Ther. 1974 Oct;191(1):32-44.

Mechanisms of drug biotransformation reactions in the placenta.胎盘中药物生物转化反应的机制。

Fed Proc. 1972 Jan-Feb;31(1):48-51.

Induction of cytochrome P450 isozymes by phenobarbital in pregnant rat and fetal livers and placenta.苯巴比妥对孕鼠、胎肝及胎盘细胞色素P450同工酶的诱导作用。

Exp Mol Pathol. 2005 Apr;78(2):150-5. doi: 10.1016/j.yexmp.2004.07.002.

3,4-Benzpyrene and aniline are hydroxylated by human fetal liver but not by placenta at 6-7 weeks of fetal age.3,4-苯并芘和苯胺在胎儿6至7周龄时可被人胎儿肝脏羟基化，但不能被胎盘羟基化。

Biochem Pharmacol. 1973 Jun 15;22(12):1538-40. doi: 10.1016/0006-2952(73)90336-5.

The rate of aniline metabolism in vivo in rats exposed to aniline and drugs.暴露于苯胺和药物的大鼠体内苯胺的代谢速率。

Xenobiotica. 1975 Aug;5(8):511-9. doi: 10.3109/00498257509056121.

[Studies on drug demethylation in fetal liver].[胎儿肝脏中药物去甲基化的研究]

Dtsch Med Wochenschr. 1969 Jun 6;94(23):1232 passim. doi: 10.1055/s-0028-1111200.

Oxidative drug metabolism in the perinatal rabbit liver and placenta. A biochemical and morphologic study.围产期兔肝脏和胎盘的氧化药物代谢。一项生化与形态学研究。

Xenobiotica. 1973 Jan;3(1):37-48. doi: 10.3109/00498257309151498.

引用本文的文献

Drug transfer and metabolism by the human placenta.药物在人胎盘的转运与代谢。

Clin Pharmacokinet. 2004;43(8):487-514. doi: 10.2165/00003088-200443080-00001.

Maternal drug abuse and human term placental xenobiotic and steroid metabolizing enzymes in vitro.孕期药物滥用与足月人胎盘外源性生物活性物质及类固醇体外代谢酶

Environ Health Perspect. 2000 Feb;108(2):141-5. doi: 10.1289/ehp.00108141.

Environmental influences on human foetal and placental xenobiotic metabolism.环境对人类胎儿及胎盘外源性物质代谢的影响。

Eur J Clin Pharmacol. 1980 Jul;18(1):17-24. doi: 10.1007/BF00561474.

Lipoperoxidation rates and drug-oxidizing enzyme activities in the liver and placenta of some mammal species during the perinatal period.围产期一些哺乳动物物种肝脏和胎盘的脂质过氧化率及药物氧化酶活性

Experientia. 1976 Oct 15;32(10):1311-3. doi: 10.1007/BF01953111.

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