Duffy G J, D'Auria D, Brien T G, Ormond D, Mehigan J A
Br Med J. 1973 Mar 24;1(5855):712-4. doi: 10.1136/bmj.1.5855.712.
A radiopharmsceutical product, labelled macroaggregates of albumin (M.A.A.), which is in use as a lung scintiscanning agent has been noted to have an affinity for venous thrombi. With this material and an inexpensive portable scintillation detector we have attempted to diagnose and localize thrombi in leg veins. The procedure is performed at the bedside and the result is available in 30 minutes. Thirty-one patients with clinical evidence suggestive of deep venous thrombosis in the legs were studied by the radioisotope method and by phlebography. There was agreement in 18 of 21 legs shown to contain thrombus on phlebography and in 9 of 10 legs shown to be free of thrombosis on phlebography. There was, however, lesser agreement on the site of thrombosis between the two methods. The ease of performing the test combined with the rapidity of obtaining results and accuracy in diagnosis suggests that the test has a clinical application.
一种放射性药物产品，标记为白蛋白大颗粒聚合体（M.A.A.），用作肺部闪烁扫描剂，已被发现对静脉血栓有亲和力。利用这种物质和一台廉价的便携式闪烁探测器，我们试图诊断并定位腿部静脉血栓。该程序在床边进行，30分钟内即可得出结果。通过放射性同位素法和静脉造影术对31例有腿部深静脉血栓形成临床证据的患者进行了研究。在静脉造影显示有血栓的21条腿中，有18条腿两种方法的结果一致；在静脉造影显示无血栓的10条腿中，有9条腿两种方法的结果一致。然而，两种方法在血栓形成部位的一致性较低。该检测方法操作简便，结果获取迅速且诊断准确，表明该检测方法具有临床应用价值。
