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Pharmacokinetics of trichloroethanol and metabolites and interconversions among variously referenced pharmacokinetic parameters.

作者信息

Garrett E R, Lambert H J

出版信息

J Pharm Sci. 1973 Apr;62(4):550-72. doi: 10.1002/jps.2600620404.

DOI:10.1002/jps.2600620404
PMID:4698974
Abstract
摘要

相似文献

1
Pharmacokinetics of trichloroethanol and metabolites and interconversions among variously referenced pharmacokinetic parameters.三氯乙醇及其代谢产物的药代动力学以及各种引用的药代动力学参数之间的相互转化。
J Pharm Sci. 1973 Apr;62(4):550-72. doi: 10.1002/jps.2600620404.
2
Measurement of chloral hydrate, trichloroethanol, trichloroacetic acid and monochloroacetic acid in the serum and the urine by gas chromatography.
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Effect of trichloroethanol and of chloral hydrate on the in vivo rate of disappearance of ethanol in mice.三氯乙醇和水合氯醛对小鼠体内乙醇消失速率的影响。
Arch Int Pharmacodyn Ther. 1973 Apr;202(2):392-401.
4
Metabolism of trichloroethylene in man. I. The significance of trichloroethanol in long-term exposure conditions.
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Interaction of chloral hydrate and ethanol in man. I. Metabolism.
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6
Gas chromatographic analysis of trichloroethanol, chloral hydrate, trichloroacetic acid, and trichloroethanol glucuronide.
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[Toxicological-chemical findings by a lethal poisoning with chloral hydrate].
Arch Toxikol. 1970;27(1):67-70.
8
The salivary secretion and clearance in the horse of chloral hydrate and its metabolites.
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NTP technical report on the toxicity and metabolism studies of chloral hydrate (CAS No. 302-17-0). Administered by gavage to F344/N rats and B6C3F1 mice.国家毒理学计划关于水合氯醛(化学物质登记号:302-17-0)毒性和代谢研究的技术报告。通过灌胃法给予F344/N大鼠和B6C3F1小鼠。
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The kinetics of chloral hydrate metabolism in mice and the effect thereon of ethanol.
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Pediatric chloral hydrate poisonings and death following outpatient procedural sedation.门诊程序镇静后小儿水合氯醛中毒与死亡
J Med Toxicol. 2014 Jun;10(2):219-22. doi: 10.1007/s13181-013-0358-z.
2
The actions of ether, alcohol and alkane general anaesthetics on GABAA and glycine receptors and the effects of TM2 and TM3 mutations.醚类、醇类和烷类全身麻醉药对γ-氨基丁酸A型(GABAA)和甘氨酸受体的作用以及跨膜区2(TM2)和跨膜区3(TM3)突变的影响。
Br J Pharmacol. 2000 Feb;129(4):731-43. doi: 10.1038/sj.bjp.0703087.
3
Binding of propofol to blood components: implications for pharmacokinetics and for pharmacodynamics.
丙泊酚与血液成分的结合:对药代动力学和药效学的影响。
Br J Clin Pharmacol. 1999 Jan;47(1):35-42. doi: 10.1046/j.1365-2125.1999.00860.x.
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Alkyl halides, super hydrogen production and the pathogenesis of pneumatosis cystoides coli.卤代烃、氢气过度产生与结肠气囊肿的发病机制。
Gut. 1997 Dec;41(6):778-84. doi: 10.1136/gut.41.6.778.
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Alpha subunit isoform influences GABA(A) receptor modulation by propofol.α亚基异构体影响丙泊酚对GABA(A)受体的调节。
Neuropharmacology. 1997 Jul;36(7):941-9. doi: 10.1016/s0028-3908(97)00074-9.
6
The interaction of trichloroethanol with murine recombinant 5-HT3 receptors.三氯乙醇与小鼠重组5-羟色胺3受体的相互作用。
Br J Pharmacol. 1995 Apr;114(8):1641-51. doi: 10.1111/j.1476-5381.1995.tb14952.x.
7
Therapeutic assessment of chloral hydrate premedication for pediatric dentistry.水合氯醛用于儿童牙科术前用药的治疗评估
Anesth Prog. 1984 Sep-Oct;31(5):191-6.
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Computer-assisted mechanistic structure-activity studies: application to diverse classes of chemical carcinogens.计算机辅助的机理结构-活性研究:应用于各类化学致癌物
Environ Health Perspect. 1985 Sep;61:69-96. doi: 10.1289/ehp.856169.
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Evaluation of hepatic dysfunction in endotoxin pretreated rats using tolbutamide as a marker.以内毒素预处理大鼠,用甲苯磺丁脲作为标志物评估肝功能障碍。
Eur J Drug Metab Pharmacokinet. 1990 Jul-Sep;15(3):203-9. doi: 10.1007/BF03190205.
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Simultaneous determination of trichloracetic acid and trichlorethanol by gas chromatography.
Int Arch Occup Environ Health. 1976 Mar 9;36(4):235-41. doi: 10.1007/BF00409354.